Kluyveromyces marxianus CBS 6556 growing cells as a new biocatalyst in the asymmetric reduction of substituted acetophenones

…, C D'Introno, FM Perna, MG Perrone, A Scilimati

文献索引：Vitale, Paola; D'Introno, Cinzia; Perna, Filippo Maria; Perrone, Maria Grazia; Scilimati, Antonio Tetrahedron Asymmetry, 2013 , vol. 24, # 7 p. 389 - 394

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被引用次数: 7

摘要

The use of microorganism growing cells is a well recognized methodology in biocatalyzed organic reactions. A non-conventional thermotolerant Kluyveromyces marxianus yeast strain was used for the bio-reduction of different arylketones. Differently substituted ketones were converted into the corresponding (S)-alcohols with up to 96% enantiomeric excess under very mild reaction conditions. Kluyveromyces marxianus represents a promising ...