Synthesis, neurotoxicity and anticonvulsant study of some benzothiazole analogs
KK Sethi, SM Verma, N Prasanthi…
文献索引：Sethi, Kalyan K.; Verma, Saurabh M.; Prasanthi, Naru; Annapurna, Mathrusri M. Letters in Drug Design and Discovery, 2011 , vol. 8, # 9 p. 774 - 777
A series of benzothiazole sulfonamides, thiosemicarbazones and guanidine derivatives were synthesized by different pathways and tested for the neurotoxicity studies by the Rotarod method. The minimal motor impairment, the significant results were found with compounds (7) and (3). Some of these compounds also showed anticonvulsant activity by decreasing the duration of convulsions in albino mice. Compound (3),(7) and also ...
