Tetrahedron letters

Facile synthesis of substituted nitrilotriacetamides

…, S Cramer, S Sucheck, E Skrzypczak-Jankun

文献索引：Smith; Cramer; Sucheck; Skrzypczak-Jankun Tetrahedron Letters, 1992 , vol. 33, # 50 p. 7765 - 7768

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被引用次数: 8

摘要

Abstract Ligands which contain multiple amide groups represent interesting possibilities as chelating agents. We report here a facile synthesis and crystal structure of nitrilotriacetamide, 2, a neutral tetradentate ligand which we have been studying for metal complexation. Also described herein is a divergent synthesis of the mono-, di-and trimethylated and dimethyl-monoalkyl derivatives of 2.