Continuous chemoselective methylation of functionalized amines and diols with supercritical methanol over solid acid and acid-base bifunctional catalysts
T Oku, Y Arita, H Tsuneki, T Ikariya
文献索引：Oku, Tomoharu; Arita, Yoshitaka; Tsuneki, Hideaki; Ikariya, Takao Journal of the American Chemical Society, 2004 , vol. 126, # 23 p. 7368 - 7377
The selective N-methylation of bifunctionalized amines with supercritical methanol (scCH3OH) promoted by the conventional solid acids (H-mordenite, β-zeolite, amorphous silica-alumina) and acid-base bifunctional catalysts (Cs-P-Si mixed oxide and γ-alumina) was investigated in a continuous-flow, fixed-bed reactor. The use of scCH3OH in the reaction of 2-aminoethanol with methanol (amine/CH3OH= 1/10.8) over the solid catalysts ...
