A pyrazolylamine??phosphonate monoester chelator for the fac??[M (CO) 3]+ core (M= Re, 99mTc): synthesis, coordination properties and biological assessment
…, F Figueira, JDG Correia, PD Raposinho…
文献索引：Palma, Elisa; Oliveira, Bruno L.; Figueira, Flavio; Correia, Joao D. G.; Raposinho, Paula D.; Santos, Isabel Journal of Labelled Compounds and Radiopharmaceuticals, 2007 , vol. 50, # 13 p. 1176 - 1184
Abstract Aiming to develop new strategies for the labeling of hydroxyl-containing biomolecules with the organometallic core fac-[99m Tc (CO) 3]+, we have prepared a new model bifunctional chelator, L4 (ethyl hydrogen (2-{[2-(3, 5-dimethyl-1H-pyrazol-1-yl) ethyl] amino} ethyl) phosphonate), combining a pyrazolyl-amine chelating group and a monophosphonate ethyl ester function (–P (O) OHOEt). The phosphonate group allows ...
