Synthesis of substituted 8-aminoquinolines and phenanthrolines through a Povarov approach

…, S Chandrasekaran, D Bonnet-Delpon

文献索引：De, Kavita; Legros, Julien; Crousse, Benoit; Chandrasekaran, Srinivasan; Bonnet-Delpon, Daniele Organic and Biomolecular Chemistry, 2011 , vol. 9, # 2 p. 347 - 350

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被引用次数: 14

摘要

The synthesis of 8-aminoquinolines and 1, 10-phenanthrolines with substituents in α of the nitrogen has been performed through an inverse-demanding aza-Diels–Alder (Povarov reaction) in the fluoroalcohols TFE or HFIP. This path involves simple starting materials: 1, 2- phenylenediamines, enol ethers and aldehydes.