Identification of glycogen synthase kinase-3 inhibitors with a selective sting for glycogen synthase kinase-3α

F Lo Monte, T Kramer, J Gu, UR Anumala…

文献索引：Mazzone; Bonina; Arrigo Reina Farmaco, Edizione Scientifica, 1977 , vol. 32, # 6 p. 414 - 429

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被引用次数: 25

摘要

... Volume: Page: ... are ATP competitive inhibitors and all of them inhibit the two isoforms, GSK-3α and GSK-3β, with similar potency.(6) The design ... 2 ) resulted in the oxadiazoles 4A–C.(30, 31) The heterocyclic derivatives 5a–c, 6a–c, and 7a–c(32) were prepared ...