Studies in the Imidazolone Series. The Synthesis of a Lower and a Higher Homolog of Desthiobiotin and of Related Substances1

R Duschinsky, LA Dolan

文献索引：Duschinsky; Dolan Journal of the American Chemical Society, 1946 , vol. 68, p. 2350,2353

全文：HTML全文

被引用次数: 52

摘要

In general the reaction is applicable to secondary amines that readily form an N-methylol derivative with formaldehyde. Diphenylamine and similar very weakly basic amines which do not readily form N-methylol derivatives with formaldehyde fail to react. The formaldehyde used is preferably in the form of an aqueous 30-37% solution, but may also be used in the form of paraformaldehyde.