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Journal of Organic Chemistry 2011-08-19

Total synthesis of a CD-ring: side-chain building block for preparing 17-epi-calcitriol derivatives from the Hajos-Parrish dione.

Karol Michalak, Jerzy Wicha

文献索引:J. Org. Chem. 76(16) , 6906-11, (2011)

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摘要

An efficient synthesis of the key building block for 17-epi-calctriol from the Hajos-Parrish dione involving a sequence of diastereoselective transformation of the azulene core and the side-chain construction is presented.

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