Preparation of functionalized organoindium reagents by means of magnesium insertion into organic halides in the presence of InCl3 at room temperature

S Bernhardt, ZL Shen, P Knochel

文献索引：Bernhardt, Sebastian; Shen, Zhi-Liang; Knochel, Paul Chemistry - A European Journal, 2013 , vol. 19, # 3 p. 828 - 833

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被引用次数: 11

摘要

The conversion of organic halides to organometallics by direct metal insertion (the Grignard reaction) is a very general method. The LiCl-mediated insertion of Mg,[1] Zn,[2] Al,[3] Mn,[4] and In [5] has proven to be especially effective and provides access to a range of functionalized organometallic reagents that can readily be applied to cross-coupling [6] and other reactions with electrophiles.[7] Nevertheless, some functionalized halides, such as 4 ...