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Substituted arylmethyl phenyl ethers. 1. A novel series of 5-lipoxygenase inhibitors and leukotriene antagonists

…, UR Chakraborty, S Sciortino, RJ Gordon…

文献索引:Musser; Chakraborty; Sciortino; Gordon; Khandwala; Neiss; Pruss; Van Inwegen; Weinryb; Coutts Journal of Medicinal Chemistry, 1987 , vol. 30, # 1 p. 96 - 104

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被引用次数: 50

摘要

There are several examples in the literature of rationally designed inhibitors of 5-LO. Common approaches involve the preparation of acetylenic,'allenic? aryl: or dimethyllo analogues of AA. Other approaches include the synthesis of analogues of 5- ...

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