Investigation of steapsin lipase for kinetic resolution of secondary alcohols and synthesis of valuable acetates in non-aqueous reaction medium

…, KM Deshmukh, YS Wagh, RS Singhal…

文献索引：Dhake, Kishor P.; Deshmukh, Krishna M.; Wagh, Yogesh S.; Singhal, Rekha S.; Bhanage, Bhalchandra M. Journal of Molecular Catalysis B: Enzymatic, 2012 , vol. 77, p. 15 - 23

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被引用次数: 10

摘要

In present study, the application of steapsin lipase (as a biocatalyst) was investigated for kinetic resolution of secondary alcohols (1-phenyl ethanol and their derivatives) using vinyl acetate as an activated acyl donor. The enzymatic protocol was optimized for various reaction parameters such as effect of the molar ratio, solvent, temperature, time and biocatalyst loading to obtain best reaction conditions. On optimization, developed ...