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Journal of heterocyclic chemistry

The reaction of N??aminophthalimide with isothiocyanates

MJ Hearn, LE Lucas

文献索引:Hearn, Michael J.; Lucas, Laura E. Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 615 - 616

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被引用次数: 12

摘要

Abstract N-Aminophthalimide (I) reacted in refluxing isopropyl alcohol with a number of isothiocyanates to give the related 1: 1 addition products, N-(3-substitutedthioureido) phthalimides III. On the other hand, heating I directly with an excess of neat arylisothiocyanates produced the N-arylphthalimides IV. As shown for IIIa, the 1: 1 addition products are conveniently deblocked by the Ing-Manske procedure to yield the 4- ...