Journal of Heterocyclic Chemistry

Preparation of some 4??hydroxyl??1??methyl??1H??2, 1??benzothiazine??3??carboxanilide 2, 2??dioxides

JG Lombardino

文献索引：Lombardino,J.G. et al. Journal of Heterocyclic Chemistry, 1972 , vol. 9, p. 315 - 317

全文：HTML全文

被引用次数: 26

摘要

Abstract An improved, 3-step synthesis of 3, 4-dihydro-1-methyl-1H-2, 1-benzothiazin-4-one 2, 2-dioxide has been developed. This general method offers a more facile entrance into the 2, 1-benzothiazine 2, 2-dioxide heterocyclic system than was heretofore available. Preparation of several 3-carbox-anilides was accomplished by interaction of this ring system with various isocyanates. The resulting carboxanilides are moderately strong, enolic acids.