Synthesis of [2H, 13C]??Labelled Diallylmalonates− Useful Probes for the Study of Transition Metal??Catalysed 1, 6??Diene Cycloisomerisation

KL Bray, GC Lloyd??Jones

文献索引：Bray, Katharine L.; Lloyd-Jones, Guy C. European Journal of Organic Chemistry, 2001 , # 9 p. 1635 - 1642

全文：HTML全文

被引用次数: 9

摘要

Abstract Reliable synthetic routes to isotopically labelled dimethyl [13 C, 2 H] diallylmalonates (1) have been developed. Dimethyl diallylmalonates readily undergo transition-metal catalysed cycloisomerisation and the isotopically labelled substrates are expected to be of general utility in the study of the mechanism of such reactions. In the synthetic routes developed, the 2 H labelled allyl chains were introduced by reduction of ...