Friedel–Crafts Benzylation of Activated and Deactivated Arenes

G Schäfer, JW Bode

文献索引：Schaefer, Gabriel; Bode, Jeffrey W. Angewandte Chemie - International Edition, 2011 , vol. 50, # 46 p. 10913 - 10916

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被引用次数: 22

摘要

The Friedel–Crafts alkylation of aromatic compounds is a versatile method for CÀC bond formation from unactivated CÀH bonds.[1] Despite the power and historical importance of Friedel–Crafts reactions, the poor reactivity of deactivated aromatic compounds, the difficultly of employing even modestly deactivated alkyl halides, and complications from the aluminum by-products have encouraged the development of new aromatic ...