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Tricyclic pharmacophore-based molecules as novel integrin α v β 3 antagonists. Part IV: Preliminary control of α v β 3 selectivity by meta-oriented substitution

D Kubota, M Ishikawa, M Ishikawa, N Yahata…

文献索引:Bioorganic and Medicinal Chemistry, , vol. 14, # 12 p. 4158 - 4181

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被引用次数: 13

摘要

... Bioorganic & Medicinal Chemistry. ... Pharmaceutical Research Department, Meiji Seika Kaisha, Ltd, 760 Morooka-cho, Kohoku-ku, Yokohama 222-8567, Japan. Received 30 November 2005, Revised 26 January 2006, Accepted 27 January 2006, Available online 28 February ...