Journal of Dental Research 1993-10-01

Transport of sugars, including sucrose, by the msm transport system of Streptococcus mutans.

L Tao, I C Sutcliffe, R R Russell, J J Ferretti

文献索引：J. Dent. Res. 72(10) , 1386-90, (1993)

全文：HTML全文

摘要

The range of substrates transported by the sugar-binding protein-dependent msm (multiple sugar metabolism) system of S. mutans was investigated. By determining the ability of unlabeled sugar to compete with radiolabeled melibiose transport, we have demonstrated that the transported sugars included a number of carbohydrates structurally related to raffinose. A model accommodating these results has been devised which accounts for the sugars transported by the msm transport system. Competition with radiolabeled melibiose transport indicated sucrose to be an msm substrate. This was confirmed by examination of uptake of radiolabeled sucrose in scrAB mutants lacking the sucrose-specific phosphotransferase system.