Microwave Michaelis–Becker synthesis of diethyl phosphonates, tetraethyl diphosphonates, and their total or partial dealkylation

D Meziane, J Hardouin, A Elias, E Guénin…

文献索引：Meziane, Dalila; Hardouin, Julie; Elias, Abdelhamid; Guenin, Erwann; Lecouvey, Marc Heteroatom Chemistry, 2009 , vol. 20, # 6 p. 369 - 377

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被引用次数: 27

摘要

Abstract Diethyl phosphonates and tetraethyl alkyldiphosphonates were efficiently and rapidly prepared via the Michaelis–Becker reaction, under microwave irradiation. These compounds were then hydrolyzed to phosphonic and diphosphonic acids or selectively monodealkylated to give monoesters of phosphonic acids and symmetrical diethyl esters of diphosphonic acids. These reactions were also achieved rapidly in satisfactory yields with ...