Organic letters

Silica gel promotes reductions of aldehydes and ketones by N-heterocyclic carbene boranes

T Taniguchi, DP Curran

文献索引：Taniguchi, Tsuyoshi; Curran, Dennis P. Organic Letters, 2012 , vol. 14, # 17 p. 4540 - 4543

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被引用次数: 18

摘要

N-Heterocyclic carbene boranes (NHC-boranes) such as 1, 3-dimethylimidazol-2-ylidine trihydridoborane (diMe-Imd-BH3) serve as practical hydride donors for the reduction of aldehydes and ketones in the presence of silica gel. Primary and secondary alcohols are formed in good yields under ambient conditions. Aldehydes are selectively reduced in the presence of ketones. One, two, or even all three of the boron hydrides can be transferred. ...