Pyrrole chemistry. XXVI. A synthesis of porphobilinogen from pyrrole

…, HJ Anderson, CE Loader, K Faber

文献索引：Demopoulos, Basil J.; Anderson, Hugh J.; Loader, Charles E.; Faber, Kurt Canadian Journal of Chemistry, 1983 , vol. 61, p. 2415 - 2422

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被引用次数: 39

摘要

A synthetic strategy has been developed which enables pyrrole to be used as the starting material for the synthesis of 2, 3, 4-trisubstituted pyrroles of the type used to construct porphyrins. The total synthesis of porphobilinogen has been accomplished as a demonstration of the applicability of the approach.