1-(1, 2, 5-Thiadiazol-4-yl)-4-azatricyclo [2.2. 1.02, 6] heptanes as New Potent Muscarinic M1 Agonists: Structure-Activity Relationship for 3-Aryl-2-propyn-1-yloxy and 3 …
L Jeppesen, PH Olesen, L Hansen…
文献索引:Journal of Medicinal Chemistry, , vol. 42, # 11 p. 1999 - 2006
... Journal of Medicinal Chemistry. ... Chemistry. The syntheses of the azatricyclic thiadiazoles 8a−h and 9a−h began with the known 1-cyano-4-azatricyclo[2.2. 1.0 2,6 ]heptane 14 (Scheme 2), which is obtained by reaction ...
[Parmar, Dixit; Matsubara, Hiroshi; Price, Kieran; Spain, Malcolm; Procter, David J. Journal of the American Chemical Society, 2012 , vol. 134, # 30 p. 12751 - 12757]