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Folate antagonists. 17. Synthesis and biological properties of a 2, 4??diamino??6??thioquinazoline analog of aminopterin

LM Werbel, L Newton…

文献索引:Journal of Heterocyclic Chemistry, , vol. 17, # 3 p. 497 - 500

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被引用次数: 6

摘要

... ».o2c-f\ss/Aco^ 2 HCl -> Ho2c-r ^Vsh+ciY/ Yno2 •oo Chemistry. The route to 2 is shown in Schemes I and II. ... Heterocyclic Chem., 17, 501 (1980). ... 1562 to the Army Research Program in malaria. (3) EF Elslager, P. Jacob, J. Johnson, LM Werbel, DF Worth and L. Rane, J. Med. ...