Pteridines. V. Some analogs of 4, 7-diamino-2-phenyl-6-pteridinecarboxamide

J Weinstock, RY Dunoff, JG Williams

文献索引：Weinstock,J. et al. Journal of Medicinal Chemistry, 1968 , vol. 11, # 3 p. 542 - 548

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被引用次数: 1

摘要

A scries (it'4,'i-di~ miiio-ti-pteridirie~ ar~~~) xaniide~ were prepared either hj-reactii) ii of the appropriate 2-3uhtituted 4, 6-diamiiio-j-iiitrosopy~ imidine with the required Y-wbstituted cyaiioacelamide 01'by aminolysis of ethyl 4,'i-diamino-2-pheriyl-6-pteridinecart~ oxyl~~ te, The ester waq prepared from ethyl tlia1nino-~-nitroso-2-pheii~ lpyri~ iidirie aid alho iinexpec. led1. v ohtaiiietl when the treated with diphenyl sulfoacetate, cyaiioac rea, ur c~~ ...