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Tetrahedron

Préparation et conversion D'ω-formylalkylphosphonates en acides aminocarboxyalkylphosphoniques

…, G Fabre, F Sauveur, N Collignon, P Savignac

文献索引:Varlet, J. M.; Fabre, G.; Sauveur, F.; Collignon, N.; Savignac, Ph. Tetrahedron, 1981 , vol. 37, p. 1377 - 1384

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被引用次数: 40

摘要

ω-Formylalkylphosphonates by acid hydrolysis of the corresponding acetals obtained from triethylphosphite and bromoacetals has been described. In aqueous solution in the presence of cyanide and amines these compounds give aminonitriles (Strecker) or hydantoins (Bucherer). These reactions give access to a large variety of compounds which by acid hydrolysis (Strecker) or basic then acid hydrolysis (Bucherer) lead to pure ...