Organic & Biomolecular Chemistry 2016-03-21

Catalytic selective deuteration of halo(hetero)arenes.

Manojkumar Janni, S Peruncheralathan

文献索引：Org. Biomol. Chem. 14 , 3091-7, (2016)

全文：HTML全文

摘要

Deuterium labeled aromatic and heteroaromatic compounds are synthesized in good to excellent yields with >98% deuterium purity via palladium catalyzed deuterodehalogenation reaction using commercially available and inexpensive reagents. Selective deuteration of bromoaniline is also demonstrated without H/D exchange in an amino N-H group.