Synthesis, antimicrobial and antiviral evaluation of substituted imidazole derivatives

D Sharma, B Narasimhan, P Kumar, V Judge…

文献索引：Sharma, Deepika; Narasimhan, Balasubramanian; Kumar, Pradeep; Judge, Vikramjeet; Narang, Rakesh; De Clercq, Erik; Balzarini, Jan European Journal of Medicinal Chemistry, 2009 , vol. 44, # 6 p. 2347 - 2353

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被引用次数: 101

摘要

In the present study, we have synthesized 2-(substituted phenyl)-1H-imidazole (1–12) and (substituted phenyl)-[2-(substituted phenyl)-imidazol-1-yl]-methanone (13–26) analogues and screened them for their antimicrobial activity against Gram positive, Gram negative and fungal species. The results of antibacterial study indicated that compounds 15, 17 and 24 showed appreciable antibacterial activity and compound 26 emerged as the most ...