Tetrahedron letters

New syntheses for 11-(mercaptoundecyl) triethylene glycol and mercaptododecyltriethyleneoxy biotin amide

CA Canaria, JO Smith, CJ Yu, SE Fraser, R Lansford

文献索引：Canaria, Christie A.; Smith, Jeffrey O.; Yu; Fraser, Scott E.; Lansford, Rusty Tetrahedron Letters, 2005 , vol. 46, # 28 p. 4813 - 4816

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被引用次数: 17

摘要

Novel syntheses for mercaptododecyltriethyleneoxy biotin amide and 11-(mercaptoundecyl) triethylene glycol are presented here. Such alkyl thiols are popular components in creating monolayers capable of specifically binding proteins. The development of a variety of functionalized alkyl thiol compounds has a great impact on biosensor substrate design. In our synthesis of mercaptododecyltriethyleneoxy biotin amide, we couple ...