Synthesis of a Key Intermediate for the Synthesis of (+)-Grandisol Utilizing (-)-Quinic Acid.

K Matsuo, M Morita, K Kawashima

文献索引：Matsuo, Keizo; Morita, Masakatsu; Kawashima, Ken-Ichi Chemical and Pharmaceutical Bulletin, 1997 , vol. 45, # 11 p. 1734 - 1738

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被引用次数: 3

摘要

November 1997 mercury lamp under continuous bubbling of ethylene gas, but the desired cyclobutane derivative 9 was not obtained and the starting 8 was recovered.” Therefore, we decided to construct the cyclobutane ring in a stepwise mode, and conjugate addition of an allyl group to the enone 8 was examined. The results are summarized in Table 1. When 8 was treated with allylmagnesium bromide in the presence of copper(I) bromide~~~dimethyl sulfide complex (CuBr- MeZS), ...