Quantitative structure-activity relationships of antibacterial agents, 7-heterocyclic amine substituted 1-cyclopropyl-6, 8-difluoro-4-oxoquinoline-3-carboxylic acids.

岡田哲夫，江角清志，山川眞透，佐藤久夫…

文献索引：Chemical and Pharmaceutical Bulletin, , vol. 41, # 1 p. 126 - 131

被引用次数: 33

摘要

... activity; logP; parabolic relationship The last three decades in medicinal chemistry have been ... R6 R7 X R1 verifying relationships between antibacterial activity and chemical structure, markedly ... length and width and the level of unsaturation of © 1993 Pharmaceutical Society of ...