A novel synthesized tyrosinase inhibitor:(E)-2-((2, 4-dihydroxyphenyl) diazenyl) phenyl 4-methylbenzenesulfonate as an azo-resveratrol analog
…, P Chun, NH Park, HR Moon, HY Chung
文献索引：Bae, Sung Jin; Ha, Young Mi; Kim, Jin-Ah; Park, Ji Young; Ha, Tae Kwun; Park, Daeui; Chun, Pusoon; Park, Nam Hee; Moon, Hyung Ryong; Chung, Hae Young Bioscience, Biotechnology and Biochemistry, 2013 , vol. 77, # 1 p. 65 - 72
Abstract We synthesized a novel series of (E)-2-((substituted phenyl) diazenyl) phenyl 4- methylbenzenesulfonate derivatives (2 and 3) and (E)-2-((substituted phenyl) diazenyl) phenol derivatives (4 and 5), and conducted an evaluation in order to determine their inhibitory effects on mushroom tyrosinase, with the aim of discovering a tyrosinase inhibitor. Most of the compounds (3–5) exhibited higher inhibitory effects than kojic acid (IC 50= ...
