A New Synthesis of Pteridines Substituted with Branched and Linear Alkenyl Groups at C (6). The Nitroso??Ene Reaction of 4??(Alkenoylamino)??5??nitrosopyrimidines
…, WB Schweizer, M Xu, A Vasella
文献索引：Zhang, Fang-Li; Schweizer, W. Bernd; Xu, Ming; Vasella, Andrea Helvetica Chimica Acta, 2007 , vol. 90, # 3 p. 521 - 534
Abstract Pteridines substituted with a 1, 1-, 1, 2-, or 1, 1, 3-substituted alkenyl group (mostly (E)-configured) at C (6) were synthesized in high yields by the intramolecular nitroso-ene reaction of 4-(alkenoylamino)-2-amino-6-benzyloxy-5-nitroso-and 4-(alkenoylamino)-2, 6- diamino-5-nitrosopyrimidines. Thus, the N-alkenoyl nitrosopyrimidines 4 and 5 provided the pteridines 6 and 7, respectively, characterized by a 1, 2-disubstituted (E)-alkenyl ...
