PPA-Mediated C–C Bond Formation: A Synthetic Route to Substituted Indeno [2, 1-c] quinolin-6 (7 H)-ones

X Liu, Q Zhang, D Zhang, X Xin, R Zhang, F Zhou…

文献索引：Liu, Xu; Zhang, Qian; Zhang, Dingyuan; Xin, Xiaoqing; Zhang, Rui; Zhou, Fenguo; Dong, Dewen Organic Letters, 2013 , vol. 15, # 4 p. 776 - 779

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被引用次数: 14

摘要

A facile and efficient synthesis of substituted indeno [2, 1-c] quinolin-6 (7 H)-ones from a variety of α-acyl N-arylcinnamamides mediated by polyphosphoric acid (PPA) is described, and a mechanism involving the formation of a dicationic superelectrophile and subsequent double intramolecular nucleophilic cyclization reactions is proposed.