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Novel 5, 8??Diazabenzo [c] phenanthrenes: Synthesis and Mutagenicity

M Upton, MI JAEDA, C UPTON

文献索引:Upton, Mathew; Jaeda, Moussa I.; Upton, Christopher Journal of Pharmacy and Pharmacology, 1998 , vol. 50, # 5 p. 475 - 482

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被引用次数: 5

摘要

Abstract The polycyclic aromatic hydrocarbons have been recognized as carcinogens and mutagens since the early part of this century. More recently their aza and polyaza derivatives have been shown to have the same biological activity. A major source of these compounds is the combustion of fresh or metamorphosed plant materials; this contributes to the environmental burden of, and exposure to, these carcinogens. We report the synthesis ...