Tetrahedron letters

Domino 'Michael-retro-Michael-aldol'reactions of 1, 3-bis-silyl enol ethers with 3-formylchromones

P Langer, B Appel

文献索引：Langer, Peter; Appel, Bettina Tetrahedron Letters, 2003 , vol. 44, # 43 p. 7921 - 7923

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被引用次数: 21

摘要

Functionalized benzophenones are of considerable interest as pharmacologically relevant natural products and natural product analogues and represent versatile synthetic building blocks. 1. and 2. Classical syntheses of benzophenone derivatives mainly rely on the Friedel–Crafts acylation. 3 However, unsatisfactory results are frequently obtained when this method is applied to the synthesis of functionalized or substituted derivatives. Major drawbacks result from ...