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Efficient synthesis of functionalized 1, 2, 3-triazoles by catalyst-free 1, 3-dipolar cycloaddition of nitroalkenes with sodium azide

T Wang, XC Hu, XJ Huang, XS Li…

文献索引:Wang, Ting; Hu, Xiao-Chun; Huang, Xu-Jiao; Li, Xin-Sheng; Xie, Jian-Wu Journal of the Brazilian Chemical Society, 2012 , vol. 23, # 6 p. 1119 - 1123

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被引用次数: 10

摘要

Five-membered nitrogen heterocycles play an important role in biological systems. Among these, the 1,2,3-triazoles and their derivatives are of considerable interest as they possess a wide range of biological properties, such as anti-HIV, 1 anti-allergic, 2 anti-fungal, 3 anti-viral 4 and anti-microbial activity. 5 1,2,3-Triazoles are important in pharmacological applications due to its stability toward light, moisture, oxygen, and metabolism in the body. 6 In ...