Organic letters

New Polyhydroxylated Pyrrolidines Derived from Enantiopure 3, 6-Dihydro-2 H-1, 2-oxazines

R Pulz, A Al-Harrasi, HU Reissig

文献索引：Pulz, Robert; Al-Harrasi, Ahmed; Reissig, Hans-Ulrich Organic Letters, 2002 , vol. 4, # 14 p. 2353 - 2355

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被引用次数: 69

摘要

Diastereoselective hydroborations of enantiopure 3, 6-dihydro-2 H-1, 2-oxazines led to dihydroxy-substituted 1, 2-oxazines. Samarium diiodide-induced NO bond cleavage generated 1, 4-amino alcohols which were recyclized to polyhydroxylated pyrrolidines which are potential glycosidase inhibitors.