Interaction of pentafluorobenzoylpyruvic acid and its esters with N-nucleophiles. Synthesis of 4-oxoquinoline-2-carboxylic acids

VI Saloutin, ZE Skryabina, PN Kondrat'ev…

文献索引：Saloutin, V. I.; Skryabina, Z. E.; Basyl', I. T.; Kondrat'ev, P. N.; Chupakhin, O. N. Journal of Fluorine Chemistry, 1994 , vol. 69, # 1 p. 119 - 126

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被引用次数: 9

摘要

Abstract Nitrogen-substituted 4-oxoquinoline-2-carboxylic acids have been prepared by the reaction of pentafluorobenzoylpyruvic acid with isopropyl-, cyclohexyl-, phenyl-and ethanol- amine. Ammonia and triethylamine, however, were found to react with pentafluorobenzoylpyruvic acid to form only the 2-carboxy-5, 6, 7-8-tetrafluorochromone; such behaviour has been found in the reactions of ethyl pentafluorobenzoylpyruvate with ...

~66%

~65%

Synthesis of 2 (3)-ethoxycarbonyl-5, 6, 7, 8-tetrafluorochro...

[Saloutin, V. I.; Skryabina, Z. E.; Bazyl, I. T.; Chupakhin, O. N. Russian Chemical Bulletin, 1993 , vol. 42, # 2 p. 322 - 325 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1993 , # 2 p. 362 - 364]

Reaction of pentafluorobenzoylpyruvic acid with amines

[Saloutin, V. I.; Bazyl', I. T.; Skryabina, Z. E.; Kondrat'ev, P. N.; Chupakhin, O. N. Russian Chemical Bulletin, 1994 , vol. 43, # 2 p. 279 - 282 Izvestiya Akademi Nauk, Seriya Khimicheskaya, 1994 , # 2 p. 299 - 302]