Synthesis of flavones with hypolipidemic activity

…, YK Vasilenko, MM Khachatryan, AI Pyshchev

文献索引：Oganesyan, E. T.; Vasilenko, Yu. K.; Khachatryan, M. M.; Pyshchev, A. I. Pharmaceutical Chemistry Journal, 1989 , vol. 23, # 11 p. 927 - 931 Khimiko-Farmatsevticheskii Zhurnal, 1989 , vol. 23, # 11 p. 1353 - 1356

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摘要

In a goal-oriented search for hypolipidemic flavones, we have made a selection of structural features governing this type of activity. Of considerable importance in this respect is information on the hypolipidemic activity of the thyroid hormone, thyroxine. It is well known that the search for thyroxine analogs in respect of function led to the discovery of the antisclerotic aryloxyalkanoic acids [2, 14, 16], which include the currently-used misclerone ...