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Interaction of p-fluorofentanyl on cloned human opioid receptors and exploration of the role of Trp-318 and His-319 in μ-opioid receptor selectivity

C Ulens, M Van Boven, P Daenens, J Tytgat

文献索引:Journal of Pharmacology and Experimental Therapeutics, , vol. 294, # 3 p. 1024 - 1033

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被引用次数: 26

摘要

... analogs, including designer drugs, have been synthesized, knowledge of their pharmacology is often ... To investigate the pharmacological profile of the ligands used in this study, heterologous ... This provides experimental proof for the hypothesis that a π-π interaction between Trp ...