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Journal of heterocyclic chemistry

Novel tetracyclic spiropiperidines. II. Synthesis of 2??aryl??2, 3??dihydrospiro [benzofuran??3, 4′??piperidines]

HH Ong, MN Agnew

文献索引:Ong, Helen H.; Agnew, Marc N. Journal of Heterocyclic Chemistry, 1981 , vol. 18, p. 815 - 820

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被引用次数: 6

摘要

Abstract A series of 2-aryl-2, 3-dihydropsiro [benzofuran-3, 4′-piperidines] has been synthesized as potential psychotropic agents via an efficient intramolecular fluorine displacement reaction. Treatment of a key intermediate, 4-cyano-4-(2-fluorophenyl)-1-