Practical, highly convergent, asymmetric synthesis of a selective PPARγ modulator

PE Maligres, GR Humphrey, JF Marcoux…

文献索引：Organic Process Research and Development, , vol. 13, # 3 p. 525 - 534

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被引用次数: 19

摘要

... Organic Process Research & Development. ... Process Res. Dev. ... Acylation of indole 5 was accomplished using a slightly modified procedure from Okauchi and co-workers.(26) Treatment of indole 5 with Et 2 AlCl (1.2 equiv) and p-chlorobenzoyl chloride (1.2 equiv) in a mixture of ...