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An improved microwave assisted one-pot synthesis, and biological investigations of some novel aryldiazenyl chromeno fused pyrrolidines

NJ Parmar, BR Pansuriya, HA Barad, R Kant…

文献索引:Parmar, Narsidas J.; Pansuriya, Bhavesh R.; Barad, Hitesh A.; Kant, Rajni; Gupta, Vivek K. Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 12 p. 4075 - 4079

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被引用次数: 8

摘要

An improved microwave assisted one-pot method for the synthesis of twelve new aryldiazenylchromeno [4, 3-b] pyrrolidines via intramolecular azomethine ylide cycloaddition route is described. The method is efficient and advantageous over conventional and solvent- free thermal methods. The stereochemistry of the compounds was confirmed on the basis of various NMR experiments, and finally by single crystal X-ray diffraction data. N-Methyl or ...