Facile transformation of Biginelli pyrimidin-2 (1H)-ones to pyrimidines. In vitro evaluation as inhibitors of Mycobacterium tuberculosis and modulators of cytostatic …

K Singh, K Singh, B Wan, S Franzblau…

文献索引：European Journal of Medicinal Chemistry, , vol. 46, # 6 p. 2290 - 2294

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被引用次数: 51

摘要

... European Journal of Medicinal Chemistry. ... IR (KBr): ν max 3350, 1750, 1650, 650 cm −1 . 1 H NMR (300 MHz, CDCl 3 , 25 °C): δ 1.44 (t, J = 7.2 Hz, 3H, ester–CH 3 ), 2.84 (s, 3H, C6–CH 3 ), 4.42 (q, J = 7.2 Hz, 2H, ester–CH 2 ), 9.02 (s, 1H, C4–H). 13 C NMR (75 MHz, CDCl 3 ...