Boron analogs of amino acids. 3. Synthesis of (ethylcarbamoyl) borane adducts of trimethylamine, dimethylamine, methylamine, and ammonia

BF Spielvogel, FU Ahmed, KW Morse…

文献索引：Spielvogel, Bernard F.; Ahmed, Fahim U.; Morse, Karen W.; McPhail, Andrew T. Inorganic Chemistry, 1984 , vol. 23, p. 1776 - 1777

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被引用次数: 26

摘要

(0) NHEt (l), is a precursor in the synthesis of Me3N-BH2COOH, the protonated boron analogue of the dipolar amino acid betaine3+ Me3NCH2COO-. Both Me3N. BH2COOH and its ethylcarbamoyl derivative have demonstrated significant antitumor and antihyperlipidemic activity in Also, the trimethylamine (ethy1carbamoyl) borane showed significant antiinflammatory and antiarthritic activities in animal model studiesa6 Because ...