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A Microwave??Assisted Domino Benzannulation Reaction towards Functionalized Naphthalenes, Quinolines, and Isoquinolines

Y Wang, C Tan, X Zhang, Q He, Y Xie…

文献索引:Wang, Yuqin; Tan, Cun; Zhang, Xiaofei; He, Qian; Xie, Yuyuan; Yang, Chunhao European Journal of Organic Chemistry, 2012 , # 33 p. 6622 - 6629,8

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被引用次数: 3

摘要

Abstract An efficient palladium/copper-catalyzed domino reaction was developed to yield functionalized naphthalenes, quinolines, and isoquinolines. The reactions of various substituted 1-phenylprop-2-yn-1-ols containing electron-donating (EDG) and electron- withdrawing (EWG) groups and 1-heteroarylprop-2-yn-1-ols worked well with this procedure. Both electron-rich and-deficient aryl halides were satisfactory substrates for this reaction. ...