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Tetrahedron

Delineating ligand effects in intramolecular aryl amidation reactions: formation of a novel spiro-heterocycle by a tandem cyclisation process

EL Cropper, AP Yuen, A Ford, AJP White, KKM Hii

文献索引:Cropper, Emma L.; Yuen, Aui-Ping; Ford, Agnes; White, Andrew J.P.; (Mimi) Hii, King Kuok Tetrahedron, 2009 , vol. 65, # 2 p. 525 - 530

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被引用次数: 16

摘要

Ligand effects for intramolecular Pd-catalysed aryl amidation reaction were examined for the synthesis of seven-membered benzolactam rings. In an attempt to produce an eight- membered ring, tandem C–N/C–O bond forming reactions occurred to give a novel spiro- benzofuran-lactam structure.