The synthesis of a series of thiazolyl and benzothiazolyl hydrazones derived from α-(N)- acylpyridines,-quinolines,-isoquinolines,-pyridazines,-pyrimidines, and-pyrazines is reported. The stereochemistry of these compounds was determined by NMR spectroscopic methods. The antiproliferative activity of the novel compounds was quantified in tissue culture (melanoma, breast carcinoma, colon adenocarcinoma, epitheloid cervix carcinoma ...
