Tetrahedron

Fluorophore-linked zinc (II) dipicolylamine coordination complexes as sensors for phosphatidylserine-containing membranes

C Lakshmi, RG Hanshaw, BD Smith

文献索引：Lakshmi; Hanshaw, Roger G.; Smith, Bradley D. Tetrahedron, 2004 , vol. 60, # 49 p. 11307 - 11315

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被引用次数: 68

摘要

A series of Zn2+–2, 2′-dipicolylamine (Zn2+–DPA) coordination complexes with an attached NBD fluorophore are synthesized and evaluated as fluorescent sensors. The sensors do not respond to vesicles composed of zwitterionic phosphatidylcholine, but the NBD fluorescence emission is enhanced in the presence of anionic vesicles. A sensor with two Zn2+–DPA units and a hydrophilic tris (ethyleneoxy) linker produced a larger ...