In the search for new anticancer drugs. 26. A comparison of anticancer activities of several tepa, thio??tepa, seleno??tepa, and azetidine analogs, including congeners …
G Sosnovsky, J Lukszo, M Konieczny…
文献索引：Sosnovsky; Lukszo; Konieczny; Purgstaller; Laib Journal of Pharmaceutical Sciences, 1994 , vol. 83, # 7 p. 982 - 988
Abstract A series of TEPA, Thio-TEPA, Seleno-TEPA, and azetidine analogs, including congeners containing an aminoxyl moiety, were synthesized and evaluated in vivo for anticancer activity against the murine lymphocytic leukemia P388. All aziridine derivatives were found to be active with an increase in life span ranging from 42% to 272%, and all azetidine analogs were rated as inactive with one marginal exception. An attempt was ...
